Natural IVF


Natural IVF is an appealing idea to the infertility patients who are considering in-vitro fertilization (IVF) to conceive. Natural cycle IVF consists of a procedure that retrieves a single egg created during the natural menstrual cycle and refrains the use of a drug to stimulate pregnancy.

Natural cycle IVF uses minimal stimulation IVF or mini IVF, which gradually reduces the number of drugs used for fertility. Generally, natural IVF involves low doses of hormones to stimulate egg production, aiming for nearly 2-4 eggs. The natural cycle IVF do not use hormone injection to promote multiple egg production involving the least dose of clomiphene citrate, for 10-12 days before the egg retrieval.

Vatsalya is the best IVF fertility center in Nepal offering natural cycle in vitro fertilization (IVF). The natural cycle IVF is less expensive and is nearly a pure natural IVF treatment.

What is Natural IVF treatment?

Natural cycle IVF is similar to standard IVF, in which very little medication is used to stimulate the female ovaries. Also known as the “Drug-Free IVF”, the patients do not need to inject gonadotropins on a daily basis.

In standard IVF, drugs are injected once a week or more to stimulate the ovaries and to mature the eggs. Unlike the standard IVF, the natural cycle patient uses only oral medication, to enhance the natural development of ovarian follicles and prepare the eggs for harvesting. The purpose of using oral medication in natural IVF treatment is to select robust and quality eggs for retrieval.

On completion of the medicinal procedure, an injection is given to trigger ovulation for proper harvesting of eggs, which sums up the whole natural IVF treatment.

Eligible candidates for natural IVF treatment

  • Women above 35-years of age.
  • Women preferring to limit drug intake during their fertility treatment.
  • Women failing to produce egg follicles when stimulated by hormones.
  • Women identified with the risk of Ovarian Hyper Stimulation Syndrome (OHSS).
  • Women suffering or undergoing cancer treatment.
  • Patients who do not want to freeze embryos or eggs.
  • Patients not seeking to deal with multiple eggs or embryos after IVF treatment. 
  • Women with more than two failed fertility treatments.
  • Those suffering from genetic disorders, family issues, or has some history.
  • Women experiencing more than one miscarriage.

4 steps of Natural cycle IVF

1. Preparing for the natural IVF treatment

Before commencing with the modified natural cycle IVF, an initial evaluation is conducted to obtain information about the reproductive health and disease-causing infertility. The couple needs to take the assessment within three to six months before starting the natural IVF cycle treatment. 

For women, the assessment comprises of:

  • Blood test for infertility assessment.
  • Transvaginal ultrasound (TVS)
  • Pelvic examination
  • Hysterosalpingogram (HSG)

For men, the assessment consists of:

  • Semen analysis
  • Blood tests for hemoglobin, VDRL, Anti-HCV, and more.

2. Hormonal level monitoring

Women will have a vaginal ultrasound to determine the blood tests and the size of the follicles. The monitoring is done to confirm the right kind of treatment and natural cycle IVF steps that needs to be taken for the upcoming treatment session.

3. Collection of sperm and ovum

Under deep sedation, egg collection shall be performed by the embryologist. Patients must stay in the hospital for further observation after surgery. Whereas for men, sperm is collected onsite to maintain the temperature of the sperm sample.

4. Preimplantation genetic screening (PGS)

It refers to the techniques which examine the chromosol and genetics abnormalities. The PGS for the natural IVF treatment includes an examination of next-generation sequencing (NGS) and Mitochondrial DNA testing.

We, at Vatsalya Natural IVF, Kathmandu, take care of every procedure involved in the natural IVF treatment. Patients willing to experience pregnancy in their late years, without any worry can step into our fertility clinic and take benefit from the expert consultation service and treatments at an affordable price. 

Advantages of natural cycle IVF

For a natural cycle IVF success, the patient requires no or less medication with less monitoring. As the ovaries are being naturally treated, the pair do not need to wait for a longer period of time in between the treatments, before beginning another natural cycle IVF treatment. Therefore, the cumulative natural IVF success rates can be similar to conventional IVF or higher than the traditional IVF success stories. Other advantages of natural IVF treatments include:

  • Conceiving with own eggs

    For a woman with blocked or damaged fallopian tubes, natural cycle IVF provides the best opportunity of conceiving a child using their own eggs. Natural alternatives to IVF (traditional) are taken to facilitate the natural IVF cycle with frozen embryos instead of laboratory techniques.
  • Patients with low ovarian reserve

    Natural IVF success stories include achievements of older women with low ovarian reserve. Natural IVF treatment focus on the quality of eggs, rather than quantity.
  • Unexplained fertility

    1 in 6 pair go through fertility problem and sometimes the reason for such infertility remain unidentified and remains undiagnosed after thorough investigation. These patients may reap benefits from the modified natural cycle IVF without any intervention.
  • Male infertility

    Men with infertility problem after taking the natural IVF cycle treatment holds a higher success rate of conceiving with IVF instead of natural methods. Hospitals for natural IVF have experienced consultants to properly advise men with fertility problems and offer genuine solutions to overcome infertility issues.
  • Premature Ovarian Failure

    Women suffering from menopause or premature ovarian failure can reap the benefits of natural IVF cycle treatment using donor eggs. Further, the Natural cycle IVF success rates over 40, hence, females even after attaining 40 years of age or menopause can take help from natural IVF treatment to plan a healthy family.
  • PCOS

    A common condition where hormonal imbalance leads to an irregular menstrual cycle. IVF has proven to be successful in patients with PCOS who refrain from ovulation induction. 

Natural IVF cost in Nepal

The natural cycle IVF cost depends on the individual circumstances and on the personalized plans, which shall be further explained by the experts of a natural fertility clinic. Vatsalya is the best natural IVF clinic offering several natural IVF treatment packages to help the patient in planning their treatment cost. If you wish to find out more, please contact us!

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